Multiple myeloma is a cancer that arises from white blood cells known as plasma cells causing a reduction in the production of normal blood cells by the bone marrow resulting in an immune system dysfunction, and damage to the kidneys and the bones.
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Multiple myeloma is a blood cancer that affects white blood cells known as plasma cells, and causes the formation of abnormal plasma cell accumulation in the bone marrow.
Multiple myeloma doctors say that multiple myeloma is not a common blood cancer. It is more commonly seen in the older age group and is more common in men than in women.
Anybody can be affected by multiple myeloma, but the condition is more commonly seen in the elderly age group, male gender, black race, those with a family history of multiple myeloma, and a history of a condition called MGUS or monoclonal gammopathy of undetermined significance.
In an individual with multiple myeloma, mutations in the DNA of plasma cells cause the production and multiplication of abnormal plasma cells. These plasma cells begin to accumulate in the bone marrow and prevent the production of normal plasma cells that are essential for the formation of antibodies that fight infections.
Multiple myeloma symptoms include:
Multiple myeloma results when there is a mutation in the plasma cells within the bone marrow, which leads to the development of abnormal plasma cells that multiply at a rapid rate and begin to accumulate in the bone marrow, reducing the production of normal plasma cells.
Hematologists diagnose multiple myeloma based on symptoms, medical and family history, clinical examination to evaluate symptoms and overall health, and investigations such as blood tests to look for M proteins and beta 2 microglobulin proteins that are released by the abnormal plasma cells, urine analysis for M proteins, bone marrow aspiration and biopsy, and imaging tests such as X-rays, and CT/MRI/PET scans.