Breast pain or mastalgia is the tenderness of breast tissue that may be present in both men and women due to some underlying factors. Throbbing, sharp pain may occasionally occur and can range from being milder to severe symptoms. A stabbing or burning pain with feeling of tightness in the breast tissue can indicate underlying abnormalities of breast tissue or heart anomalies. This can affect one or both breasts. In women this may be due to normal physiological changes associated with menstrual cycle ranging for one full week or longer each month, mostly starting just before a period occurring through the menstrual cycle. In men however, breast pain is caused by high amounts of fat deposition in breast gland tissue referred to as gynecomastia. This results in an imbalance of the estrogen and testosterone hormone levels. Other than that transgender women experience breast pain when they are taking hormone replacement therapy to enlarge breast tissue.
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