Systemic Lupus Erythematosus (SLE), also known as Lupus, is a chronic autoimmune disorder in which the body’s immune system attacks its organs. The immune system of one’s body attacks its healthy tissue causing widespread tissue damage and inflammation. Systemic Lupus Erythematosus can affect the skin, joints, kidneys, brain, and various other organs. It is the most common type of lupus. It can range from mild to life-threatening conditions. It occurs in all age groups including children; however, it mostly occurs in women in the adolescent and postmenopausal age group.
Systemic Lupus Erythematosus is not a medical emergency and is a long-term disorder.
The primary cause of Systemic Lupus Erythematosus is genetic mutations. Other factors include environmental triggers, such as exposure to ultraviolet rays, being on certain medications, viruses, trauma, or stress, exposure to chemical and pollutants can also result in the development of SLE. It affects more women when compared to men and it is believed that hormonal changes also play a role in the development of the condition.
A positive family history of Systemic Lupus Erythematosus in at least one first degree relative such as parents or siblings increases the risk of developing the disorder. Hormonal changes and being on certain medications can also increase the risk of developing the condition.
Individuals having Systemic Lupus Erythematosus may sometimes have worsening episodes and sometimes have mild episodes. Symptoms change with time. Some of the signs and symptoms that an individual experiences include the following.
In some individuals, symptoms flare up and sometimes go away. Therefore, individuals have periods of flare-ups as well as remissions.
A thorough physical examination of the body is done to identify the symptoms related to Systemic Lupus Erythematosus:
Other diagnostic studies include the following:
It is difficult to diagnose because symptoms resemble many other conditions. Therefore, findings on a thorough physical examination along with results of the investigation tests are considered while establishing a diagnosis of Systemic Lupus Erythematosus.
There is no treatment for Systemic Lupus Erythematosus. Treatment only focuses on controlling symptoms. The goal of the treatment of the condition is to prevent organ damage and achieve complete remission.
Medical treatment includes:
Since the exact cause of the condition is not known, it cannot be prevented. Patient education, physical and lifestyle measures play a vital role in Systemic Lupus Erythematosus management. The following measures can help to lead a better life by controlling the symptoms.
Consume a healthy diet:
It causes damage to all systems in the body. Some of the complications that are associated with this condition include:
Most of the individuals with Systemic Lupus Erythematosus live a normal life with treatment. The prognosis varies from person to person. The overall outcome of the disease is highly variable ranging from permanent remission to death. In recent times, the survival rate of individuals suffering from SLE has increased from 5 years to 10 years.
Treatment of Systemic Lupus Erythematosus is effective when it is started in the early stages of the disease. Therefore, it is always recommended to consult a physician after noticing any of the symptoms associated with the condition.
Treatment is provided on an outpatient basis and does not require any hospitalization.