Dengue fever also known as break bone fever is a mosquito-borne viral infection with flu-like characteristics. The virus is transmitted through mosquitoes and ticks. Dengue fever occurs in regions with tropical and sub-tropical climates.
It is classified into two types depending on the intensity of the symptoms.
Uncomplicated Dengue Fever: A fever associated with mild symptoms that resolve within a week is termed as uncomplicated dengue fever.
Severe Dengue or Dengue Hemorrhagic Fever: Fever associated with severe internal bleeding, plasma leakage, or organ dysfunction is termed as dengue hemorrhagic fever. This is subdivided into IV grades. The last two grades are termed as Dengue Shock Syndrome. Shock is a phase that can lead to low blood pressure and organic failure.
Dengue fever is caused by one of the four dengue viruses.
The four dengue virus serotypes are DENV-1, DENV-2, DENV-3, and DENV-4. The virus is spread through a mosquito species, called Aedes. These kinds of mosquitoes are daytime biters. They would be active in the hours before sunrise and during sunset.
Risk factors that influence the development of dengue fever are:
Signs and symptoms of dengue fever develop 3 to 14 days after being infected. They include:
In a few cases, symptoms worsen and can lead to a severe form of dengue fever called severe dengue or dengue hemorrhagic fever. This causes low platelet count and bleeding. It can further progress to dengue shock syndrome where blood pressure drops drastically becoming life-threatening. Some of the signs and symptoms of these conditions include:
An individual who has suffered dengue fever once is at an increased risk of experiencing more severe symptoms if infected again.
A diagnosis of dengue fever is made based on medical history, clinical evaluation, and the results of blood tests. Low white cell count, low platelets, and increased hematocrit level usually indicate positive dengue fever.
Dengue fever is quite difficult to diagnose because its symptoms are more similar to other viral illnesses like malaria or typhoid. A complete physical examination is performed considering both the medical and travel history of an individual.
A complete blood test is done to evaluate the levels of white blood cells, platelets, and hematocrit.
The course of the dengue fever is divided into three phases:
Febrile: At this phase, an individual suffers from high fever potentially up to 104 degrees Fahrenheit associated with muscle and joint pains, headache, nausea, and dehydration. A type of skin rash also develops. This phase lasts for 4 days.
Critical: At this phase, platelets count in the blood declines rapidly, and white blood cell count decreases. Symptoms include abdominal pain, vomiting, bleeding from the gums and nose, mild fluid accumulation in the body, and increased skin rash. The critical phase of dengue fever is called dengue hemorrhagic fever. This state can further progress to dengue shock syndrome which can lead to death. This phase lasts for 2 to 3 days.
Recovery: The last phase of dengue is recovery. The leaked fluids are reabsorbed into the bloodstream and the platelets count is restored. This phase lasts for 4 days; however, the weakness in the body can last for many weeks.
There is no specific treatment for dengue fever. There are no particular antiviral drugs to treat the disease. The treatment focuses on reducing the symptoms. Taking rest and consuming plenty of liquids is recommended to avoid dehydration.
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The primary preventive measure for dengue fever is to avoid mosquito bites
A critical phase of dengue fever can lead to complications like internal bleeding, shock, and organ dysfunction. Some of the complications associated with dengue fever are:
Diagnosing and treating dengue fever at an early stage can result in complete recovery and a good prognosis. Nevertheless, in a critical phase of dengue fever, there is a possibility of excessive internal bleeding, irreversible shock, and organ impairment leading to a life-threatening condition and death.