Thalassemia :
Thalassemia refers to an inherited blood disorder that affects the body's ability to produce healthy hemoglobin and red blood cells. Thalassemia is categorized into two types, depending on the affected gene, namely, alpha thalassemia and beta thalassemia. The symptoms of this blood condition in the mild to moderate stage include growth problems, delayed puberty, bone abnormalities like an enlarged spleen and osteoporosis. The presenting complaints of thalassemia in the severe stage include severe anemia and other symptoms like pale or yellowish skin, poor appetite, irregular bone structure in the face, and urine that is dark or tea colored. Thalassemia is diagnosed by conducting investigations such as CBC, reticulocyte count, hemoglobin electrophoresis, iron studies and genetic testing. The treatment modalities to manage thalassemia involve giving folic acid supplements, blood transfusions, iron chelation, luspatercept injection and bone marrow and stem cell transplant.











