Sickle Cell Disease :
Sickle cell disease is described as an inherited blood disorder, due to which the red blood cells form into a sickle shape. The presenting complaints of sickle cell disease are episodes of severe pain- mainly in the legs, back, arms and also chest region, paleness, fatigue, weakness, yellowish skin and white part of the eyes, painful, swollen hands and feet and swollen joints and stroke in severe cases. Genetic variation is the major factor responsible for causing sickle cell disease. Based on these types of variations, sickle cell disease is categorized into various types such as hemoglobin SS (HbSS), hemoglobin SC (HbSS), sickle cell beta thalassemia (HbS/beta-thal) and other rare forms of sickle cell disease. The potential complications of sickle cell disease include anemia, acute chest syndrome, blood clots (deep vein thrombosis and pulmonary embolism), leg ulcers, liver, kidney and heart damage, avascular necrosis, dactylitis, pulmonary hypertension, priapism, sleep apnea, stroke, vision loss and other vision complaints.











