It is through anti-malarial medications and the kind of antimalarial medication used depends on the type and severity of the disease. Simple or uncomplicated malaria can be treated with oral medications, ACT or artemisinin combination therapy which uses artemisinin in combination with antimalarial drugs such as piperaquine, amodiaquine, mefloquine, etc, In the first trimester of pregnancy quinolones plus clindamycin is used, whereas ACT is used in the second and third trimester. Severe and complicated malaria is treated with intravenous antimalarial therapy using artemisinins and quinolones and monitoring the individual in a critical care unit.
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Malaria is caused when plasmodium parasites are transmitted to humans through the bite of female Anopheles mosquitoes, which become infected after biting a person already infected with malaria. A detailed explanation of the causes is as follows:
The main types of malaria:
Malaria doctors explain that to prevent the spread of malaria, the following measures must be taken:
Use Mosquito Nets: Sleep under insecticide-treated bed nets to avoid mosquito bites, especially at night.
Malaria primarily affects the red blood cells, spleen, and liver. When the Plasmodium parasites enter the bloodstream, they invade and multiply within red blood cells, leading to the rupture of infected cells. This causes a release of more parasites into the bloodstream, resulting in cycles of fever, chills, and other flu-like symptoms characteristic of malaria. The spleen plays a vital role in filtering and removing damaged red blood cells, including those infected with the parasites. In malaria, the spleen may become enlarged and overactive, potentially leading to anaemia. Proper diagnosis and treatment are crucial to prevent organ damage and complications associated with malaria.
Individuals suspected of malaria should consult a healthcare professional or primary care physician. If diagnosis or treatment becomes complex or there are complications, an infectious disease specialist or a travel medicine specialist may be consulted for specialized care. Local health clinics may have specific protocols for testing and treating the disease in some regions with a high malaria prevalence.
Malaria specialists explain that malaria spreads through the bite of infected female Anopheles mosquitoes. When these mosquitoes bite a person infected with malaria, they ingest the Plasmodium parasite. The parasite then develops within the mosquito and can be transmitted to another human when the mosquito bites again. Once inside a new host, the parasites multiply in the liver and red blood cells, leading to the characteristic symptoms of malaria and enabling the cycle of transmission to continue.
Malaria treatment with appropriate antimalarial medications can ensure malaria is cured. However, a permanent cure, in the sense of developing immunity to all forms of the disease, is not typically achieved through infection and recovery. People can develop immunity after multiple infections, but this immunity may not provide complete protection, and reinfections can occur. Preventive measures, such as bed nets, insecticides, and antimalarial drugs, are crucial for controlling and reducing the risk of malaria in endemic areas.
The treatment of malaria involves the use of antimalarial medications. The medication prescribed depends on the type of Plasmodium parasite causing the infection and its sensitivity to specific drugs, as well as the patient's age, overall health, and the severity of the disease. Commonly used drugs include artemisinin-based combination therapies (ACTs) and other antimalarials like chloroquine and quinine.
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