Best Doctors for Ankylosing Spondylitis Treatment in Karimnagar

Ankylosing spondylitis is autoimmune disease associated with HLA B27 gene. It is a type of arthritis that causes inflammation in the joints and ligaments of the spine. It affects vertebrae joints causing fusing of vertebrae resulting reduced flexion. It affects other organs including eyes, aorta, lungs, ligaments. Risk factors are Age, prolong sitting, genetic-HLA B27, smoking.

Symptoms begin after age 40, Pain that can be either sharp or dull and Sudden onset with morning stiffness of up to a few hours. The pain usually becomes persistent and severe during night pain often forces the patient to rise and move around. There is no specific laboratory test for diagnosing AS .

In blood test common inflammatory marks are increased like Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), Elevated serum IgA, (Alp)Alkaline phosphatase, Anti-cyclic citrullinated peptide (CCP), Antinuclear antibodies (ANAs), Imaging Test like X Ray shows bamboo spine pattern , CT Scan , MRI. Treatment includes drugs like NSAIDs, Anti-tnf agents-infliximab, Janus kinase (JAK) inhibitors, Corticosteroid and physiotherapy, Severe disease need surgery to repair joint damage.