Best Doctors for Sickle Cell Disease Treatment in Indore

Sickle Cell Disease (SCD) is a group of inherited disorders ie,. genetic defect present which leads to the synthesis of abnormal hemoglobin leading to abnormal red blood cells that are sickle shaped/crescent shaped instead of round . Red blood cells(RBC) carry oxygen to various tissues and in case of SCD the defective RBC stick together and doesn't flow freely in the blood stream leading to decreased oxygenation to the tissues, anemia, episodes of pain (sickle cell crises), swelling in hands and feet, increased risk of infections, yellowish skin and eyes (jaundice), delayed growth and development, enlarged spleen etc. It can vary from a mild to severe depending upon the number of genes mutated ie,.sickle cell anemia (HbSS) (most severe form) and sickle cell trait (HbAS)(milder form).Complications include organ damage (kidneys, liver, spleen), stroke and neurological problems, respiratory issues, bone and joint problems etc. Management includes treating pain(medications), hydroxyurea (to reduce frequency of pain episodes and complications), blood transfusions if necessary ,regular health check-ups, avoiding triggers for pain episodes like stress, cold temperatures and other supportive care.